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Alternatively, we searched the chymotrypsin digested sample with low chymotrypsin specificity (cleavage carboxyterminal to L, M, W, F, and Y allowing a maximum of four missed cleavages).
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Alternatively, we could search the literature for other studies (if necessary, involving other tumour types or other treatment regimes) that give response rates for chemotherapy-naïve and previously treated patients.
To further understand the relationship between alternative splicing and structure we searched for alternatively spliced isozyme pairs and were able to find just five such pairs with structures determined for both partners [ 157- 161].
If both CCs were related to the same organism, we searched for those Ensembl identifiers that were included in both CCs, alternatively the ortholog gene identifier was used.
So we searched.
Alternatively, we based our search of candidate structural domains in BIGs and GBFs on the bioinformatics analysis of their own sequences, taking advantage of the growing number of sequences from fully annotated genomes from mammals, insects, plants, nematode, and fungi, to which we included our annotation of Sec7-containing proteins from the newly sequenced genome of Paramecium.
Why were we searching?
Alternatively, we could employ exhaustive search on all the combinations of local clocks but this is only possible for small data sets.
Alternatively, we can consider the equilibrium search framework of Burdett and Mortensen (1998) to understand the earnings gaps observed in the data.
Alternatively, we can use a heuristic search algorithm to approximate the local bound.
Alternatively, we can estimate the harmonic frequencies by searching for greatest maxima of in the plane.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com