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Alternatively, we decided to assess the ATP synthesis driven by substrates of both complex I (pyruvate and malate) and complex II (succinate) to investigate if and how the 2,5-HD toxic effect was mediated by inhibition of the mitochondrial respiratory chain.
Alternatively, we decided to use the reported PK/PD model describing the drug-induced neutropenia for that purpose.
Alternatively, we decided to rescreen for nitroTyr-RSs from the same initial synthetase library by modifying the process in which RSs were selected from a library of mutants.
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Alternatively, if we decide that we do want to remain a country and understand that being a country entails, among other things, affording its legal residents special rights (which is this blogger's recommendation), our policy-makers should take up the issue of immigration reform as soon as they pass health care reform.
Alternatively, if we decide that it is morally unacceptable to place blame on cancer victims for poor lifestyle choices, funding for lung, liver, and oral cancers should be increased to levels comparable to other cancers relative to their burden.
When the time comes, we could try to pay off our mortgage (assuming ours is still outstanding) and update our home, including appliances; alternatively, we might decide to sell our home in favor of a smaller, newer energy efficient model, thereby reducing monthly expenses even more.
To test this hypothesis, we decided to repeat the GOF experiments described above in cells alternatively provided with Dicer1 activity or deprived of it, by morpholino technology [55], [56].
We decided?
We decided to charge.
We decided to experiment.
We decided to marry.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com