Does stimulation of the Kir6.2/SUR2A, the cardiac-type KATP, channel by activation of PKG in intact cells (see Fig. 1) result from direct PKG phosphorylation of the channel, or alternatively, involve phosphorylation of some intermediary, regulatory protein that in turn activates the channel?
However, injury may alternatively involve the right common iliac artery, iliac veins, aorta, or inferior vena cava [ 59].
Alternatively, get involved in the increasingly large number of amateur space projects and put your name to part of a spacecraft (a topic I will be returning to in the coming weeks).
Alternatively, genes involved in multiple biological processes (or genes not involved in the disease BP in normal individuals) may not rank as highly.
M2 macrophages, activated alternatively, are involved in key processes of tumour progression, including angiogenesis, metastasis and immunosuppression [ 2].
Alternatively, being involved in the immune response, Ly6 genes evolved more rapidly than others, and might have diverged sufficiently to not be recognised by sequence similarity searches.
Importantly, it has not been conclusively resolved whether SYMRK plays an active signalling role in symbiosis or, alternatively, is involved in mechanical stress desensitisation (Esseling et al., 2004).
Alternatively, genes involved in a certain pathway or biological process can be stored as a set as well as collections of genes that are the result of an analysis performed by the user.
Earlier studies that focused on the effect of GCs on bone mass in patients with early arthritis maintained fixed low doses of GC for long periods, or alternatively, they involved a schedule that tapered the doses of these drugs from high to low doses and then withdrew the GC, or maintained it at low doses for a long period [ 18, 25].
A curated contig for a putative sterol esterase (LIPA, E.C. 3.1.1.13) may take part in the esterification of sterols with long-chain fatty acids – this enzyme may alternatively be involved in the production of ester polymers or matrix materials (34 and 35, see previous section).
