Oxidized guanines in telomeric repeats interfere with binding of the shelterin components TRF1 and TRF2 (Opresko et al., 2005), which could either directly interfere with telomere capping, or alternatively, impede telomere replication as TRF1 is critical for this process (Sfeir et al., 2009).
Alternatively, HSC70B may impede viral replication by modulating other An.
Alternatively, co-repressors that impede transcription include the nuclear receptor co-repressor (NCoR) and the silencing mediator for the retinoic acid and thyroid hormone receptor (SMRT), which interact with ligand-free ER through an elongated amino acid sequence called the CoRNR-box.
Alternatively, insert packaging could be impeded by the presence of structural anomalies, such as branched replication or recombination intermediates, within a localized region of the cpDNA.
Instead of supporting, it impedes.
Alternatively, deficient Pdx1 in duct cells might impede the generation of endocrine precursors from a latent progenitor.
One possibility for the enhanced stability of the N-terminus of NeuroD is that the N-terminal domain does not provide the unstructured region required to initiate proteasomal unfolding, or alternatively, the N-terminal domain could actively impede NeuroD degradation.
Specfically, we wanted to know if inactive β2ARs could impede internalization of active β2ARs, or alternatively if active β2ARs could promote internalization of inactive β2ARs [8], [10] [11], [11].
However, huge amount of short reads generated from RNA-Seq make the transcriptome assembly difficult, which is not only impeded by repeats but also by alternatively spliced transcripts.
Alternatively, cerebral hypoperfusion and reduced vascular pulsation may impede clearance of Aβ as it is hypothesized that motive force of vessel pulsation is required for perivascular clearance of interstitial fluid containing Aβ [ 47].
Alternatively, the removal of exogenous putrescine from the soil may impede host colonization by AMF; thus, an effective PotG gene that decreases AMF colonization of host plant will be favored by natural selection, subsequently helping X. citri pv.
