The phrase "alternatively compared to" is not correct and does not convey a clear meaning in written English.
It is not typically used because "alternatively" suggests a choice or option, while "compared to" implies a direct comparison, which creates confusion.
Example: "The results were alternatively compared to the previous study, but this phrasing is unclear."
Alternatives: "in contrast to" or "as opposed to".
Moreover, it has been demonstrated that duplicated genes are rarely alternatively spliced compared to singletons [ 4, 5].
The observation that slowly evolving genes tend to be more frequently alternatively spliced compared to moderately and rapidly evolving genes has been made in [ 16].
For the orthologous gene subset of AS genes, 17% of chicken genes are alternatively spliced, compared to 12% in human and 11% in mouse.
In all, 3901 chicken AS genes have been compared with 16715 human AS genes and 16491 mouse AS genes, suggesting that only 23% of chicken genes are alternatively spliced, compared to the human (68%) and mouse (57%) genomes.
In all, 3901 chicken AS genes have been compared with 16,715 human and 16,491 mouse AS genes, with 23% of chicken genes being alternatively spliced, compared to 68% in humans and 57% in mice.
Similarly, there was an enrichment of genes with SNVs in splice sites, UTRs and coding regions in alternatively spliced genes compared to the genes where no alternative splicing was detected.
Refining this observation further, assignment of all intronic clusters to either constitutively or alternatively spliced exons revealed that these clusters are significantly closer to alternatively spliced exons compared to constitutively spliced exons, further indicating a role of the WMM complex and mRNA m6A modification in RNA splicing as proposed previously.
Remarkably, spermatogenic cells express more alternatively spliced RNAs compared to most whole tissues; however, regulation of these RNAs remains unclear.
This dataset amounted to 16% of bovine alternatively spliced genes, compared to 16% in human and 13% in mouse.
(C) Representation of differentially alternatively spliced (DAS) genes compared to differentially expressed (DE) genes in protonemata and protoplasts (DAS_PN and DEG_PN), and protonemata and gametophores (DAS_GN and DEG_GN).
