As shown in experimental studies, the open lung concept (OLC) as an alternative ventilation strategy, improves gas exchange and reduces ventilator-induced lung injury in models of secondary surfactant deficiency [ 4, 5].
Quantitative cultures obtained by BAL was an alternative for ventilator-associated nosocomial pneumonia, particularly if the antibiotherapy was stopped before BAL performed.
While this trial galvanized a change in the management of ALI and ARDS, we reviewed it in the context of all available RCT evidence comparing the alternative approaches to ventilator management and pooled it with other trials using conservative methods.
PSV could be an interesting alternative to limit ventilator-induced diaphragmatic dysfunction.
The alternative is asynchronous ventilation with two ventilators [ 50].
Diaphragm pacing, as an alternative to a mechanical ventilator that can eliminate the need for positive pressure ventilation (PPV), has been shown to improve quality of life and extend survival in patients with advanced respiratory muscle weakness [7].
Using home ventilators (HV) may be an alternative for non-invasive ventilation in intensive care patients with respiratory failure.
An alternative approach to computing changes in ventilator settings based on simple physiological equations is to exploit the computational simulator directly.
Caution should be taken when extending this model to other hospitals where the ICU booking is much earlier than ventilator connection, or where alternative respiratory support devices are used to replace the ventilator.
