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At the April 27 meeting William Wrigley reported that Mars had increased its offer to $80 per share and had proposed an alternative termination fee structure that included a $690 million fee payable to Mars if Wrigley accepted a higher offer and a $690 million fee payable to Wrigley if the merger did not close due to the failure to receive financing.
In addition, 3'ss selection and/or the selection of poly-A additional signals help regulate alternative termination.
At this time, the mechanism by which Npl3 functions in its autoregulation by allowing the selection of an alternative termination site remains unresolved.
The differential use of exon, generated by alternative splicing events, including alternative termination and alternative promoters, generally changes some of amino acid codes of the expressed protein.
In addition to tissue-specific isoforms, profound differences in mRNA signal between tissues may also be the result of probe design and tissue-dependent alternative splicing or alternative termination.
Second, exon arrays are increasingly used to capture variation by alternative termination and alternative splicing.
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To determine the extent of transcriptional diversity in M. grisea, we assessed the proportion of the genes with alternative terminations in both libraries.
This mechanism of alternative transcription termination could define the length of 3′ extensions in fry1 and xrn3 mutant backgrounds.
Again, the results using this alternative trajectory termination criterion are in good agreement with the results obtained using the original protocol (indicated in dashed lines in Figure 7B).
The alternative transcript termination for nhr-88 is simply due to the presence of a transposable element that is sometimes included, leading to premature termination of the translational reading frame, and sometimes spliced out of the transcript.
The distribution of topologies for the EmrE, K3, nK3, and T28R mutants are computed using alternative trajectory termination criteria and compared to the distribution of topologies using the original protocol (shown in Figure 2 ).
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