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The effects of over 1600 alternative parameters were considered.
For this reason, combinations of alternative parameters were tested exploratorily (see Additional file 1) and the beneficial effects of AP were shown to be maintained or further enhanced.
eCrCl was measured every 24 h with the following formula: eCrCl (mL/minute) = (Urine Creatinine (μM or mg/dL) × Volume (mL))/(Serum Creatinine (μM or mg/dL) × Time (minutes) In addition, combinations of alternative parameters were tested exploratorily (see Additional file 1).
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However, to justify the usage of any of these alternative parameters is difficult.
In order to capture these differences objectively, an alternative parameter was defined as PSAL (see Materials and methods).
Alternative specific constants and alternative specific travel time parameters were estimated, with generic parameters estimated for journey cost and maximum travel speed [9, 10].
3.4, this model becomes an Arma 1, 1) plus noise model under the Sma1 alternative, whose parameters are not identified.
For Impute2, alternative settings of the SHAPEIT parameters were tested to identify optimal parameter settings for imputation of the whole genome (Table 3).
It perfectly fits to the patient's perception and there is lack of well-validated reliable objective alternative parameters that are commercially available to quantify the burden of chronic cough.
Branch lengths were first optimized for each data set assuming a single ω for the whole tree, and they were fixed when all other parameters were estimated under alternative models.
The ΔAIC value between null model (λ0 = λ1) and alternative model (λ0 ≠ λ1) and model parameters were then calculated.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com