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For each suggestive linkage result (HLOD≥2 for either maternal or paternal models), additional models were fit allowing for reduced penetrance or increased phenocopy rates to assess the sensitivity of the linkage signal to alternative parameters using the following procedure.
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This table shows an alternative to measuring algorithm performance with different calibration parameters, using Linnaean taxonomy to infer cluster quality.
An alternative is that it is possible to guess these parameters using the radar's polarisation and azimuth angle as a guide to possible Pareto clutter parameters.
Table 1 shows the base-case and alternatives values of parameters used in the sensitivity analysis.
Achieved results related to performed accuracy and dimension reduction are comparable with respect to other outcomes reported in the literature, and thus clearly showing that proposed methodology can be focused on finding alternative methods minimizing the parameters used for pathology diagnosing.
In addition, alternative parameter values used for the additional simulations described in Additional file 1 are shown.
In addition, alternative parameter settings used for the additional simulations described in Additional file 1 are listed.
Similar reconstructions, using alternative parameter choices, were used as basis for the findings presented in Figure 3A here.
For comparison, we aligned the simulated reads independently to the reference and alternative genomes with the same parameters used when aligning reads to the single reference genome except that zero mismatches were allowed.
The associated probabilities, as long as treatment costs, are subject to uncertainty, so it may be necessary to test robustness of the results obtained changing the model inputs or using alternative parameters.
Since this lower bound can only be derived for continuous parameters, alternative measures using the principles of detection theory are introduced for problems concerning the estimation of discrete parameters such as atomic numbers.
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