Sentence examples for alternative immune from inspiring English sources
This suggests that the initial pathophysiological hypothesis may have occulted some alternative immune changes.
In contrast, specific depletion of neutrophils via mAb 1A8 treatment did not enhance the virulence of BJx109 for B6 mice, suggesting that alternative immune defenses are sufficient to contain and clear infection.
The disease is widely believed to be caused when antibody antigen immune complexes become lodged in the kidney glomerulus, trigger proinflammatory immunologic processes, and produce organ injury (alternative immune mechanisms have also been proposed see [39], [40]).
This surprising pleiotropy establishes Notch as a key regulator of alternative immune cellular lineages in Drosophila, with important consequence for the effectiveness of defense against infection.
The difference in metallothionein expression may be due to an alternative immune response pathway since the protein has known involvement in diverse functional capacities.
Our results suggest that an alternative immune response favours retention of amyloid deposits in the brain, and switching away from this state by immunotherapy permits removal of amyloid.
Even long-term HAART is only partially efficient in preserving the humoral response in HIV+ patients, suggesting that alternative immune-modulators are required.
It is unclear whether the new battery of direct acting antiviral therapies will cure hepatitis C in all cases, especially those infected with genotype 3 viruses or with co-morbidities, such as cirrhosis and HIV co-infection (Lange et al., 2014), highlighting the need for alternative immune-based therapies.
Efforts to develop alternative immune-related response criteria (irRC) remain somewhat controversial, but further prospective validation alongside RECIST criteria, including evaluation in non immune-based therapy trials should help to establish their worth (Wolchok et al, 2009; Ribas et al, 2009; Hoos et al, 2010).
Be absent of adaptive immunity which have both specificity and memory, invertebrates seem to have evolved alternative adaptive immune strategies to resist various intruding pathogens.
We discuss how this tail-less, soluble Dscam can still play an active role in alternative adaptive immune response even while its axonal guidance functionality may be impaired.
