Like all other herpesviruses, KSHV undergoes two alternative gene expression programs throughout its lifecycle: latency and lytic replication.
This makes IVT mRNA a powerful alternative gene expression system for various applications in regenerative medicine.
This rearrangement of alternative gene segments occurs predominantly, though not entirely, at random, so that an enormous number of combinations can result.
The ancestral human population would have contained within it many genetic differences and alternative gene forms inherited from the predecessor species.
Contrasting local patterns of diversity outside the pericentromeric regions therefore also most likely reflect the outcome of selection within alternative gene pools.
As an alternative, gene traps in frizzled3 and notum/wingful, two context-independent endogenous targets, can be used as reporters.
RNA interference technology, along with several other alternative gene knockdown techniques, is now indispensable to modern biological and medical research.
A series of genome-wide molecular and biochemical studies demonstrates that SCL represses alternative gene expression in collaboration with ETO2 and the PRC1 complex at the precise time-point when multi-lineage transcriptional priming and cellular plasticity are detected.
We provide insights into the importance of considering alternative gene products when designing, undertaking, and analysing primary research, and the effect that isoforms may have on development.
The inability of baculoviral vectors to replicate in mammalian cells, their Class 1 status, and the simplicity of their construction make baculovirus an attractive alternative gene delivery vector.
Such a gene will be more likely to increase in frequency through the generations than an alternative gene that does not promote altruistic behaviour.
