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In sensitivity analyses, we evaluated effect modification by age using alternative age at explosion cut points ranging from 5 to 13 years.
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One could also estimate Fevol associated with alternative ages at maturity, alternative sizes at maturity, or alternative rates of individual growth; Fevol need not be linked solely with changes to particular ages at maturity, as illustrated here.
Alternative age estimates using Gondwana fragmentation calibrations or an alternative dating algorithm (penalized likelihood) point to an older age for this node at 20 (13 28) mya and 14 mya, respectively (Table 1).
The genotype counts, case control association, meta-analyses, alternative models, association with age-at-onset and epistatic interactions can be found in Online Resources 3 8.
Logit regression showed that the impact of the difference in risk between alternatives increased with age at the younger end of the age range.
Thus, the Downing method may be useful as a simple alternative to more complex integrated age-at-harvest models for population monitoring.
Specific provisions of legal cannabis laws (LCL) (e.g., dispensary regulations) may impact the likelihood that youth will use alternative methods and the age at which they first try the method – potentially magnifying or mitigating the developmental harms of cannabis use.
Alternative models stratifying by either age at diagnosis (continuous) or duration of diabetes or adjusting for age at diagnosis (continuous) resulted in similar risk estimates.
Cost-effectiveness ratios rise with age at vaccination; an alternative intervention that vaccinates adults with diabetes 60 years of age or older had a cost-effectiveness ratio of $2.7 million per QALY.
I wonder whether an alternative explanation, which relates to the mother's age at birth, would have given more consistent results across the two studies.
Specifically, we posited that there would be an age at which immunotherapy was a better economic alternative to life-long intranasal steroids.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com