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Becker and Galetti (2008) investigated various food and feed components for alternative adhesion of intestinal E. coli and Salmonella.
As a comparison, formulations were also created without CS aldehyde and with an alternative adhesion mediator, mucoadhesive calcium alginate particles.
Yeast cell wall products are believed to act as anti-adhesive agents and are thus able to prevent intestinal bacterial attachment by providing alternative adhesion sites to enterobacteria which contain mannose-specific type I fimbriae such as E. coli and Salmonella spp. (Ofek et al. 1977).
Furthermore, GM-1111 demonstrated the ability to block leukocytes from using RAGE as an alternative adhesion ligand.
The PECAM-1−/− phenotype resembles elements of these deletion studies which also have increased number of circulating progenitor cells, suggesting that alternative adhesion molecules can compensate in the absence of PECAM-1 expression.
L-selectin shedding and integrin dysfunction render leukocyte adhesion increasingly susceptible to shear stress and alternative adhesion receptors.
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Our results suggest that integrins (more specifically myospheroid, Drosophila's main beta integrin subunit) and integrin-containing adhesions play no role in the original attachment of these hemocytes to the dorsal patches areas, thus indicating that alternative adhesions systems may also be involved in hemocyte attachment to these locations.
Ovarian suspension could be an alternative method of adhesion prevention [9].
On the other hand, one cannot rule out that alternative steps to adhesion could be of importance in early metastasis.
However, there is growing support for an alternative hypothesis: leukocyte adhesion induced by immobilized chemokines occurs via local and spatially restricted signaling to nearby integrins.
An alternative method to reduce adhesion formation is the use of adhesion barriers.
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