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Combining both agents in an alternated schedule led to a higher and earlier reduction of tumour volume, getting significant from day 15 of treatment compared with controls (P<0.05 at days 15, 20, and 25, n=10).
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(b) Alternating therapy, using an intensive alternating schedule of myelotoxic and nonmyelotoxic drug combinations.
However, we believe that an intensive, alternating schedule represents one of the most promising approaches.
A dose intense, alternating schedule regimen, POMB/ACE developed at the Charing Cross Hospital in London has been used to treat patients with nonseminomatous MGCT since 1977.
The goal of this phase I study was to develop a novel schedule using oral etoposide and infusional topotecan as a continually alternating schedule with potentially optimal reciprocal induction of the nontarget topoisomerase.
Alternate schedules with a more favorable therapeutic index are undergoing clinical testing and should be pursued.
Because gasoline and other basic necessities were scarce immediately after the storm, the hospital placed nonessential staff on an alternating schedule.
An alternate schedule was in the works in case the labor situation was not settled, though Coughlin was clearly not enthusiastic about using it.
The panel that burned controlled a heavy track-switching device, allowing the F and G trains to move into the Bergen Street station on an alternating schedule, said Al O'Leary, a spokesman for New York City Transit.
NBC also put together an alternate schedule it could present to the advertisers in the upfront session, set for a few days away, and made sure the "Friends" cast learned of it.
Harriet ultimately decided with mingled propriety, uncertainty, and something like flirtatiousness that they could share her, on an alternating schedule, at the Taylor house, her husband entertaining guests with her on some days, and Mill on others.
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