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The alternate analyses are not meant to set policy, according to the study's authors, but to provide a "sensitivity analysis" showing how assumptions about the relationship between radiation doses and cancer drive the estimates.
Alternate analyses were performed using a cut point of ≥100 mg/dL.
Alternate analyses were performed with microalbuminuria defined as above plus use of ACE inhibitors.
Alternate analyses were also performed using a cut point of 130/8 0mmHg.
Such results will need to be confirmed by additional sequencing, alternate analyses (e.g. genome scans), and perhaps functional characterization [ 69].
Results from the original and alternate analyses were similar, and the latter results are not included in this report.
Similar(49)
Alternate statistical analyses include generalized matching by the propensity scores method and regression analyses.
We also performed alternate outcomes analyses with complete cases only, assuming participants lost to follow-up were similar to those completing follow-ups.
Alternate sensitivity analyses assumed all cases with unknown maternal HIV status were HIV-exposed or, conversely, HIV-unexposed.
Further, alternate multivariate analyses using maternal diabetes, instead of parental diabetes, gave essentially identical results (data not shown).
Combining of all alternating CID/ETD analyses of the standard protein mixture (35 000 spectra) and using default Spectrum Mill validation criteria, a total of 5 001 peptides were identified (3 235 from CID and 1 766 from ETD).
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