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Discover LudwigThe phrase "altering virus" is correct and usable in written English.
It can be used in contexts related to biology, virology, or computer science, referring to a virus that modifies or changes something.
Example: "Researchers are studying the altering virus to understand its impact on genetic material."
Alternatives: "modifying virus" or "transforming virus".
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Thus, targeting TIMP-1 may represent a potential therapeutic target to reduce pathogenesis, without altering virus clearance, during viral encephalomyelitis.
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The paper he wrote proposing the altered virus as a potential treatment for glioblastoma was rejected by two top journals before being published, in 2000.
Fitness measurements are informative per se and to plan experiments to identify the molecular basis of an altered virus behavior.
The altered virus killed human tumors implanted in mice without harming normal cells.
The altered virus would then glow green under fluorescent light as long as the virus is intact.
Other researchers say the team took a risky approach by administering high doses of the altered virus.
Wilson oversaw the trial in which 18-year-old Jesse Gelsinger died after a genetically altered virus was injected into his liver (Science, 17 December 1999, p. 2244).
Biochemist Frank McCormick and his colleagues at ONYX Pharmaceuticals in Richmond, California, found that the altered virus is unable to reproduce in normal cells, but it thrives in cancer cells lacking the p53 gene that suppresses tumor growth.
For the past 3 months, faculty and staff members at the University of Pennsylvania's Institute for Human Gene Therapy have been trying to understand why a relatively fit 18-year-old with an inherited enzyme deficiency died on 17 September, 4 days after doctors at Penn injected a genetically altered virus into his liver.
At a meeting here at the National Institutes of Health, team leader and gene therapy pioneer James Wilson said he "felt comfortable" with the decision to treat the teenager with a high dose of genetically altered virus, even though it is clear in retrospect that the viral concoction caused Gelsinger's death.
Alternatively, given that the expression of wild-type or dominant-negative forms of Akt does not significantly alter virus entry [13], [14], PI3K in the endosomes may utilize PIP3 binding factors other than Akt to regulate virus entry.
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