Sentence examples for altering the specificity from inspiring English sources

Altering the specificity of DNA-cleaving enzymes could be useful in many medical or biotechnological applications, but it is quite a challenge in terms of computational protein design.

The flexibility of the described design allows for sensor specificity change through altering the specificity of the aptamer.

Appropriate conditions were, thus, identified for coupling AMB8LK Fab' fragment to cationic emulsion without altering the specificity and affinity of the Mab fragment to the tumor antigen.

Furthermore, in the context of Cdc4alpha and cyclin E, mutational data suggest that Pin1 isomerizes a noncanonical proline-proline bond, with the possibility that Cdc4alpha may serve as a cofactor for altering the specificity of Pin1.

Several groups reported success in altering the specificity of Type IIG REases.

(vi) Synthesis of a greater diversity of beneficial peptides by selection for mutations in the acceptor stem of tRNA, altering the specificity of aminoacylation.

Modification in the structure of SAHA altered the specificity of 'δ ' towards a specific HDAC enzyme[83].

A PBP added to an in vitro assay altered the specificity of a moth pheromone receptor, making its response more specific [31].

I am also using a cell-based functional assay to test whether I can alter the specificity of particular types of clustered protocadherins by introducing mutations into the interaction interface.

A second series of reporters, activated by human rhinovirus 3C protease, demonstrated that we could alter the specificity of the reporter by reengineering the protease recognition sequence.

Variations in N-CAM activity thus do not occur by changes in the amino acid sequence that alter the specificity of binding.