Sentence examples for altering the propensity of from inspiring English sources

Accordingly, deletion in the C-terminal domain of PACAP reduces drastically the binding affinity without altering the propensity of the analogues to activate the receptor at high concentration (Bourgault et al., 2008b).

Time has not altered the propensity of some in the church to attack Islam; only these days censure is just as likely to come from a small but significant number of black majority church leaders.

Previous studies examining TREM2-triggered phagocytosis had not examined whether prior cell activation altered the propensity of TREM2 to regulate microglial phagocytosis.

There have been some successful attempts to alter the propensity of MuLV for T-cell lymphomas by using an EμMyc transgenic mouse, which results in predominantly B-cell lymphomas [231], and by expressing platelet derived growth factor B-chain (PDGFβ) from an MuLV-based retrovirus to generate mice with glioblastomas, which require activation of PDGF receptors for tumourigenesis [219].

Cyclin D acts via TGF-β-Smad signaling to alter the propensity for endoderm versus neuroectoderm fate.

Observed substitution patterns indicate that probable changes in local hydrophobicity are instrumental in altering the aggregation propensity of the peptide.

We end by proposing a set of mutations altering the swapping propensities, whose experimental characterization would contribute to refine our in silico derived hypotheses.

Trials such as RTOG 0825, which is presently open and evaluating newly diagnosed glioblastoma patients treated with standard external beam irradiation plus temozolomide versus standard external beam irradiation, temozolomide and bevacizumab, will address some of these concerns, although it may also point out the propensity of bevacizumab to alter glioma tumors to a more invasive phenotype.

Re-tuning one's strings between pieces would leave an instrument vulnerable to intonation problems, especially considering the propensity of gut strings to alter at the slightest change of climate.

Finally, the propensity of each reaction whose substrate copy counts were altered is recomputed, and the partial propensities are propagated up the propensity heap until the new R is recomputed and the cycle can be repeated.

The window of sensitivity extends prenatally to the developing foetus, as the propensity of the newborn to develop allergic eczema is altered by maternal infection or exposure to probiotic bacteria.