Sentence examples for altering the pathway from inspiring English sources

Moreover, by altering the pathway with autophagy modulators and shRNA-based suppression of Beclin1 expression, we found that inhibition of autophagy in the early as well as in the late phase of the process, largely promotes EBV transcription and replication.

An example of such a node could be a protein that—upon chemical binding blocks or amplifies estrogen-receptor signaling, altering the pathway's normal function.

Di Noia, J. & Neuberger, M.S. Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.

By altering the pathways leading to these UDP-sugars we would expect different cell wall composition [ 3, 5, 20].

In addition, and even more striking, is that the alterations observed (e.g. deletions versus amplifications) often alter the pathway output in the same direction, either all increasing or all decreasing the pathway activation.

These interventions need to dive into the heart of the process of technological development: more than the basic tick-box compliance, but tools that can actually alter the pathway of the technologies being assessed.

In humans, the Hedgehog pathway has long been known to contain genes that control fetal development and cell growth, and, when altered, the pathway can cause excessive cell growth, a hallmark of cancer.

This indicates that the Cit3− additives have significantly modified the hydrolysis behaviors of Zn2+ and Ga3+ and altered the pathway of hydrothermal reaction, though the exact mechanism yet needs clarification.

While SARM-1 regulated the least number of functional and canonical pathway genes, the highly androgenic DHT altered the pathway genes remarkably.

This demonstrates precisely how off-path reactions may alter the pathway enrichment structure.

Caregivers' narratives of their children's disease are marked by a recurrence of unexpected clinical events that alter the pathway of the disease.