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These results indicate that aging could be altering the localization of the NR2B subunit to the synaptic membrane within the frontal cortex.
The present experiments were designed to test the hypothesis that CD might function as a pro-apoptotic trigger by altering the localization of connexin 43 gap junction protein and gap junctional intercellular communication (GJIC).
When considering the deformation mode of the specimens during the cyclic loading, a permanent plastic valgus malrotation of the tibial head occurred which caused a valgus deformation of the knee, consequently altering the localization of the mechanical axis and the primary performed correction.
We then questioned whether altering the localization of Alp7 would, in turn, affect microtubule structure.
Therefore, phosphorylation at Tyr-892 may have a central role in altering the localization of beta-dystroglycan during NMJ formation [ 92– 92].
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In contrast to the observation of Myo3A/espin 1 in filopodia, Myo3A does not alter the localization of espin 1 in microvilli, and espin 1 localized throughout the microvilli, although the kinase dead Myo3A was localized at the tip of microvilli.
Second, previous studies raised concerns that AID fusion can destabilize substrate proteins4, and we observed that fusing mAID to Venus or Venus-ANAPC4 partially altered the localization of the fusion protein.
Downregulation of Arf1 expression by small interfering RNA (siRNA) decreased both the levels of HCV RNA and the production of infectious viral particles and altered the localization of NS5A to the peripheries of LDs.
By contrast, co-expression of Gn was sufficient to alter the localization of RdRp (Fig. 3B).
Thus, we determined how stress and pharmacological kinase inhibitors altered the localization of transport components.
Our data demonstrate that the absence of MSH3 does not alter the localization of MSH2 (Figure S5).
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