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The phrase "altering the interaction between" is correct and usable in written English.
You can use it when discussing changes or modifications to the way two or more entities engage or communicate with each other.
Example: "The new software is altering the interaction between users and the system, making it more intuitive."
Alternatives: "modifying the relationship between" or "changing the engagement between".
Exact(7)
At the translational level, the copy number of a protein can be fine-tuned by altering the interaction between the translation initiation region of an mRNA and the ribosome.
It is well known that soluble receptors often play an important role in cytokine signaling by stabilizing their ligand, changing concentrations of active ligand or by altering the interaction between endogenous cytokine and membrane bound ligand [32], [33].
Both substitutions are possibly altering the interaction between catalytic and regulatory subunits of calcineurin.
However, BRET analysis revealed that PKA-mediated S892 phosphorylation induces a conformational change in the receptor/KCTD12 complex without measurably altering the interaction between KCTD12 and the G-protein.
Different lysines in both histones H3 and H4 are targets for this modification, which neutralizes the basic charge of the lysine, thereby potentially altering the interaction between adjacent histones and between histones and DNA [ 41].
Since the interaction of parkin N-terminal ubiquitin-like domain with the C-terminus prevents its activation (47), it is possible that binding to the mitochondria weakens the auto-inhibition of parkin by altering the interaction between the N- and C-terminal regions.
Similar(53)
The presence of cellulose also modified these sorption properties, most likely by altering the interactions between the polymers and/or the monolignol reactions.
Altering the interactions between transport receptors and their cargo has been shown to be a major regulatory mechanism to control traffic through NPCs.
In class, she explained why cooking amounted to "altering the interactions between molecules," and how temperature, acidity, salt content and physical manipulation of ingredients all played a role in making food safe and delicious to eat.
Defects in miRNAs altering the interactions between miRNAs and their mRNA targets may contribute to schizophrenia.
Genetic changes are known to modify phenotype during evolution by altering the interactions between a protein and its ecological or biochemical environment [1] [4], by modulating existing protein-protein interactions [5], or by changing protein-DNA interactions through regulatory mutations [6] [9].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com