Sentence examples for altering the formulation from inspiring English sources

Pharmaceutical companies can remove a perfectly active drug from one indication, reformulate it in a minor way without any chemical alteration (for example modifying the dose or altering the formulation), and rebrand it for a new indication at a substantially higher price.

These results demonstrated the possibilities of modulating the release profile by means of the processing parameters rather than through the classical approach of altering the formulation.

These are a few examples of how a clinically and commercially beneficial drug product could be launched in the market by altering the formulation strategies.

To achieve equivalence, there are two general strategies which can be used to modulate aerosol output and lung deposition of pMDIs; the first is altering the formulation parameters such as propellant and excipients which we have previously reviewed [ 8, 11].

In the late 19th century Gottlob Frege of Germany, who founded modern mathematical logic, developed what is widely thought to be the most powerful argument in favour of Platonism; but he did not alter the formulation of the view.

The honeycomb architecture was modified by control of the honeycomb cell size, and hence surface area to enable control of drug release profiles without the need to alter the formulation.

This work is the first to demonstrate the feasibility of using SLS to achieve customised drug release properties of several polymers, in a swift, cost-effective process, avoiding the need to alter the formulation composition.

By altering the Hodgkin-Huxley formulation for neuronal cells to allow for trans-membrane potassium (K+) flow through two types of channels (one in which conductance falls with membrane depolarization and another in which it slowly rises), Denis Noble was able in 1960 to reproduce the AP morphology of Purkinje cells.

Altering the pharmacokinetic properties of the formulation of MEM 1414 to avoid such high Cmax concentrations of MEM 1414 may be a promising way to improve the side effect profile.

We hypothesize that by altering the dosing regimen or formulation of CQ, it might be possible to reinstate CQ into antimalarial chemotherapy by making use of this novel mechanism.

Approaches under consideration include: (a) increasing the dosage of an existing injectable formulation, (b) altering the administration or injection site, or (c) identifying drug delivery systems that could prolong the release of the drug.