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It was furthermore investigated whether modulation of HSPs and HSF1 could induce apoptosis in these cells by altering the expressions of p53, p21 and some apoptotic proteins like Bcl-2, Bax, Bid, Bad, Apaf-1 and AIF.
These findings suggest that prenatal heroin exposure during the E9 18 period enhances neuronal apoptosis by altering the expressions of caspase-3, Bcl-2, and Bax in the mouse hippocampus, and leads to impairment in hippocampus-dependent learning and memory.
Further, CNVs may result in monogenetic diseases by altering the expressions of genes flanking the CNV due to the disruption of regulatory elements [ 35, 36].
However, it remains to be determined whether altering the expressions of these genes could be use to modify seed coat color without causing unintended effects on alternative biochemical pathways.
Our transcriptome results show that the im gene reduces the degree of fiber cell wall thickness by altering the expressions of genes involved in stress responses and cellular respiration.
Regulation of the structure and function of human articular cartilage occurs by mediating other biochemical responses to mechanical strain, proteoglycan synthesis, or altering the expressions of other extra cellular matrix (ECM) proteins involved in the pathogenesis of OA [ 16, 17].
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Surprisingly, they did this without altering the expression of genes thought to be involved with the calcification process.
Thus, MSE may exert its hypocholesterolemic effect by altering the expression of HMG-CoA reductase.
This allows cancer cells to utilize a wider range of amino acids by altering the expression of a single gene.
Altering the expression of individual genes has been shown to improve grain yield in rice (Xing and Zhang, 2010).
Third, UDP-GalNAc synthesis, UDP-GlcA synthesis, and chondroitin polymerization were combinatorially optimized by altering the expression of relevant enzymes.
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