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Animal studies and protein modeling suggest that the Ile655Val polymorphism located in the transmembrane domain of the HER2 protein might influence breast cancer development by altering the efficiency of homodimerization.
Although no particular molecular function of the identified inserts has been proven at this point, we hypothesize that the observed insertions might underlie the emergence of a new regulatory interaction on the periplasmic side or might be associated with altering the efficiency of transport.
We postulate that Glu of AmTrac-LE relocates during the sensing process, most likely altering the efficiency of ESPT and in turn leading to blue and green fluorescence emission.
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Cancer cells may alter the efficiency of the antithrombotic agents.
The bioconversion process also alters the efficiency of the host response, cellular growth, material function, etc. (Azevedo and Reis 2005).
Our original hypothesis was that some of the dissolved constituents might either alter the efficiency of protein extraction or affect the quality of the extracted protein.
Neither substitution of ESBM for SSBM nor partial replacement of HMSC with beet pulp altered the efficiency of N usage for milk production or manure N excretion.
The described method quantifies how different factors in keyboard design influence both entry speed and accuracy and demonstrates that different keyboard designs can greatly alter the efficiency of keyboard use.
This might alter the efficiency of the treatment by modifying the irradiation geometry.
Also, the presence of multiple mutations and point deletions may alter the efficiency of the assay, possibly the reason for low performance in TP53 assays [16], [43].
On this note, it remains to be seen whether the 3'UTR length can be used as a marker to monitor cell reprogramming process, and whether perturbation of APA may alter the efficiency of generation of iPS cells.
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