The phrase "altering the accessibility of" is correct and usable in written English.
It can be used when discussing changes that affect how easily something can be accessed or used, often in contexts related to technology, information, or physical spaces.
Example: "The new software update is focused on altering the accessibility of the user interface to accommodate individuals with disabilities."
Alternatives: "modifying the availability of" or "changing the ease of access to".
This finding confirmed the direct role of DNA methylation in altering the accessibility of transcription factors to the NR2B promoter.
By altering the accessibility of DNA sequences, the nucleosome has profound effects on all DNA-dependent processes.
The positioning and remodelling of the nucleosomes are able to regulate the gene expression by altering the accessibility of regulatory DNA sequences to transcription factors and to the transcriptional machinery [ 36].
DNA methylation, an epigenetic modification, is known as a regulator of gene expression in cell proliferation, differentiation, and reprogramming., In general, CpG methylation was thought to silence mRNA transcription by altering the accessibility of DNA to transcriptional regulators.
Polarization of stimulated T cells with activated NFAT1 is maintained by altering the accessibility of NFAT1 to the chromatin of infg or il4 promoter in TH1 and TH2 cells, respectively [ 7].
By altering the accessibility of chromatin, it also regulates many cellular processes, including development, differentiation and proliferation (Nagl et al, 2005; Gao et al, 2008; Reisman et al, 2009).
This packaging can be distorted by epigenetic alterations and may alter the accessibility of certain regions of the genome in cancer cells.
We previously demonstrated that cocaine binding and dopamine transport alter the accessibility of Cys342 in the third intracellular loop (IL3).
As is clear from Fig. 1C, phosphorylation of these residues could alter the accessibility of substrate molecules to the catalytic groove of the deacetylase.
The results suggest that the methylation status of a specific CpG site (CRE) could alter the accessibility of its transcription factor to this site.
We speculate that the association of EphA4 with Meltrin β may alter the accessibility of endocytosis regulators to EphA4 or change their association and may prevent Vav family GEFs from activating ephrin-triggered endocytosis.
