Sentence examples for altering the accessibility from inspiring English sources

This finding confirmed the direct role of DNA methylation in altering the accessibility of transcription factors to the NR2B promoter.

By altering the accessibility of DNA sequences, the nucleosome has profound effects on all DNA-dependent processes.

The positioning and remodelling of the nucleosomes are able to regulate the gene expression by altering the accessibility of regulatory DNA sequences to transcription factors and to the transcriptional machinery [ 36].

DNA methylation, an epigenetic modification, is known as a regulator of gene expression in cell proliferation, differentiation, and reprogramming., In general, CpG methylation was thought to silence mRNA transcription by altering the accessibility of DNA to transcriptional regulators.

Polarization of stimulated T cells with activated NFAT1 is maintained by altering the accessibility of NFAT1 to the chromatin of infg or il4 promoter in TH1 and TH2 cells, respectively [ 7].

By altering the accessibility of chromatin, it also regulates many cellular processes, including development, differentiation and proliferation (Nagl et al, 2005; Gao et al, 2008; Reisman et al, 2009).

This packaging can be distorted by epigenetic alterations and may alter the accessibility of certain regions of the genome in cancer cells.

Hodges, H. C. et al. Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers.

Such modifications alter the accessibility of the DNA to other proteins and thereby demarcate transcriptionally 'active' or 'repressed' chromatin regions.

We previously demonstrated that cocaine binding and dopamine transport alter the accessibility of Cys342 in the third intracellular loop (IL3).

The impregnation of MgO on mayenite increases the surface areas and pore volume (M3 and M4) but the increase of the pore diameter is smaller compared to the Li2O impregnation case, which may alter the accessibility to the active sites.