Sentence examples for altering sensitivity from inspiring English sources

TOP2A alterations may contribute to pathogenesis in HER2+ breast carcinomas by altering sensitivity to anthracyclines [ 31].

Additionally, studies have also indicated that miRNAs play a significant role in altering sensitivity and resistance to cytotoxic treatment.

We therefore sought to examine the role of DDAH in altering sensitivity of SGHPL-4 cells to stimulation with recombinant TRAIL by independently targeting both isoforms using siRNA.

Another prevalent milk miRNA, miR-181a, regulates T-cell selection by altering sensitivity to peptide antigens, which is partly achieved through the down regulation of multiple phosphatases that act as negative regulators of T cell receptor signaling [ 53].

Fixation of these duplications indicates that they provided selective advantages presumably by leading to the recognition of an extended spectrum of viral nucleic acid structures and perhaps by altering sensitivity to viral PKR inhibitors.

Indeed, blockade of L-type calcium channels impairs insulin release by the pancreatic β-islet cells [ 15] and impairs glucose uptake by tissues by altering sensitivity to insulin [ 16, 17].

Cellular mechanisms of drug resistance arise in the cancer cell itself due to either genetic or epigenetic alterations that can alter sensitivity of the drug.

Some of these B6-sensitive substitutions also had altered sensitivity to limiting heme, another CBS cofactor.

WBR processing did not alter sensitivity, specificity, or AUC obtained at 5 min-per-view.

An Rv3371 deletion mutant of Mtb showed impaired non-replicating persistence in vitro and altered sensitivity to anti-mycobacterial drugs.

The first two are (1) that it is unbiased and (2) that the structure of the 2-IFC task does not in itself alter sensitivity.