Sentence examples for altering gene function from inspiring English sources

In the GWAS, most of the associations for the common variants are likely due to variations altering gene function in relatively subtle ways.

In this way, the diversification of individual regulatory elements allows expression to be modulated in a tissue– and/or temporal specific manner without altering gene function.

It has been documented that these elements not only contribute to the shaping and reshaping of their host genomes, but also play significant roles in regulating gene expression, altering gene function, and creating new genes.

Transposable elements are a major force in plant evolution, not only by causing genome expansions but also by altering gene function either through disruption [ 5] or acting as a raw material for new genes and novel functions [ 6, 7].

During DNA synthesis in an abnormal redox state induced by large perturbations, 8-oxoG forms a mismatched base pair with adenine, giving rise to a G : C to T : A transversion mutation, potentially altering gene function and resulting in cell death [ 3, 4, 31].

Functionally relevant CNVs can alter gene function or regulation by various proposed mechanisms, including alteration of gene dosage, gene interruption, gene fusion, and alteration of a gene's position relative to regulatory elements.

Mutations are changes in the DNA sequence that may alter gene function.

But in many cases, it is not clear how the sequence changes alter gene function — if at all.

Disruption of epigenetic processes can lead to altered gene function and malignant cellular transformation.

Multiple types of isoforms for known HSC genes and unannotated splicing that may alter gene function are presented.

Muller (1927) used x-rays to intervene on and alter gene function, thus revealing the application of methods from physics to a biological domain (see Elof Carlson on Muller's Research in Other Internet Resources).