The phrase "altering flux" is correct and usable in written English.
It can be used in contexts related to change, dynamics, or variations in a system, particularly in scientific or technical discussions.
Example: "The altering flux of energy in the system indicates a shift in the overall balance."
Alternatives: "changing flow" or "modifying current".
We describe the development of an optimized glycolytic flux biosensor and its application in detecting altered flux in a production strain and in a mutant library.
It is also recognized that changes in the function of individual lipids due to peroxidation, imbalanced fatty acid composition or their altered flux from peripheral tissues may contribute to development of atherosclerosis and diabetes [5].
These regulatory disruptions globally alter flux profiles while leaving the enzymatic network intact.
Altered glycogen metabolism and accumulation can lead to increased reactive oxygen species (ROS) and alter flux through the PPP.
This raises the intriguing possibility that large populations of cells might harbor functional heterogeneity for surviving altered flux through the proteasome.
These changes will alter flux through the endosomal pathway and ultimately place demand on autophagy and lysosomal fusion with multivesicular bodies.
Studies in Xenopus oocytes and mammalian cells provide evidence that Casp2 is metabolically regulated, acting as a sensor to changes in NADPH levels resulting from altered flux through the pentose-phosphate pathway (PPP).
In such pathways, the genes encoding the nonrate-limiting enzymes would behave as if they were in extremely long pathways because changes in their dose would not alter flux.
Thus, while we cannot fully extend haploid modeling to proteins in diploid organisms, we suggest that yeast enzymes whose knockouts alter flux balance necessitate further attention be given to their orthologous human counterparts, for both homozygous and heterozygous variations.
The decreased abundance of both enzymes is suggestive of an adaptive response that would unlikely contribute to altered flux of glycogen metabolites through the PPP and thus the low NADPH levels observed in Casp2 −/− mice.
