The phrase "altering agents such" is not correct in written English as it is incomplete and lacks clarity.
It could be used in a context where you are referring to specific types of agents that cause alterations, but it needs to be part of a complete thought.
Example: "The study focused on altering agents such as hormones and enzymes that influence cellular behavior."
Alternatives: "modifying agents like" or "agents that alter such as".
JQ1 pre-treatment alone, under these conditions, did not induce cell death in any of the cell lines tested (Supporting Information Fig S7A) nor did it significantly alter responses to genotoxic agents such as etoposide (Supporting Information Fig S7B).
However, our results demonstrate that PgP efflux can significantly alter the biodistribution of chemotherapeutic agents, such that decreased proximal uptake of drug may be counter-balanced by greater amounts of doxorubicin available to distal cells in solid tumors.
Investigations have demonstrated that cells with atypical expression of prominent proteins involved in these pathways frequently displayed altered sensitivity to DNA damaging agents such as ionizing radiation or many chemotherapeutic drugs [3].
Importantly, the imaging findings of liver metastases of GIST vary and can be altered by treatment with molecularly targeted agents such as imatinib.
The authors provide a synthesis of factors that could be associated with the emergence of novel viral agents, such as environmental change, altered human demographics, and human behavior.
The "hygiene hypothesis" is a plausible explanation for the increasing incidence of autoimmune and allergic diseases in affluent societies, but it has been difficult to directly elucidate the mechanism by which infectious agents such as nematodes alter disease-causing immune responses in humans.
Joints affected by OA exhibit increased bone turnover, which consequently increases the possibility of benefiting from drugs that alter bone metabolism, particularly the antiresorptive agents such as bisphosphonates.
DNA-damaging chemotherapeutic agents such as TMZ alter DNA at the O position of guanine and mediate their cytotoxicity at this site (Gerson, 2002).
However, MSH2 knockdown in Mpg−/− cells did not alter cellular toxicity induced by alkylating agents such as temozolomide and MMS, suggesting that alkyl adducts are not substrates for MSH2 [ 22].
Topical treatment with certain agents such as capsaicin cause altered sensory thresholds due to local sensory axon degeneration.
