The phrase "altered wider" is not correct and does not convey a clear meaning in written English.
It may be intended to describe something that has been changed to be broader or more extensive, but the phrasing is awkward and unclear.
Example: "The design was altered wider to accommodate more features."
Alternatives: "broadened" or "expanded".
Over the last decade, these three technologies have altered wide swaths of the business world, destroying and creating hundreds of billions of dollars in wealth in sectors as varied as media and transportation.
It empowered a president to sign a trade agreement before Congress voted on it with a guarantee that the executive branch can write legislation not subject to committee markup that would implement the pact and alter wide swaths of existing U.S. law.
And the Lilly drug, which may have altered a wide variety of body proteins, could have made people feel ill.
In the absence of TET2, mast cells showed disrupted gene expression and altered genome-wide 5hmC deposition, especially at enhancers and in the proximity of downregulated genes.
Non random distribution of these four groups indicated the connection of the two variables if the two experiments promoted or inhibited the same mechanism(s) that altered genome wide gene expression.
In fact, altered genome-wide ERα binding following Gen treatment is evident in endometrial cancer cells and suggests one mechanism by which E2 and Gen treatments result in different patterns of gene expression (Gertz et al. 2012).
However, despite a considerable reduction in blood and tissue folate and B12 and a significant decrease in the ratio of hepatic SAM to SAH, neither folate nor B-vitamin depletion significantly altered genome-wide cytosine methylation either in the liver or in any of the vascular tissues examined.
The radiation of five Pacific salmon from a common ancestor, additionally, could also cause significant geomorphic change by altering a wider section of the profile for a given distribution of grain sizes.
Hollande has little power to alter these wider constraints.
Here we show a direct effect of a proinflammatory cytokine on primary muscle cells that induces not only immune genes, but also alters the wider transcriptome indicating increased catabolism, lipid mobilization and decreased cell proliferation with a large role potentially for the IGFBPs.
