Sentence examples for altered widely from inspiring English sources

Pathway components, including genes and proteins, that are altered widely across individual tumors, but they often have overlapping functional consequences.

Conceptual design has been performed based on an idea in which poloidal beam injection angle can be altered widely only by a linear motion of a mirror in front of a waveguide.

Furthermore, activin A treatment of the seminoma cultures did not alter the widely used marker of CIS and seminoma cells, AP2 γ, which also contrasts previous results in TCam-2 cells in which the AP2γ transcript was significantly reduced (Young et al, 2011).

Protein engineering has produced P450 enzymes with widely altered substrate specificities, substantially increased activity and higher stability.

This altered conformation is widely thought to be responsible for the diseases, because the tangled and essentially indestructible proteins collect in brain tissue (ScienceNOW, July 29 2004).

Together, this study shows that the coordinated patterns of cortical volume network are widely altered in PD patients with a decrease in the efficiency of parallel information processing.

Protein engineering has resulted in heme and flavin monooxygenases with widely altered substrate specificities, and attempts have been reported to scale-up reactions catalyzed by these enzymes.

Analysis of the chromosomal distribution of the differentially regulated transcripts showed that the altered genes are widely spread on all chromosomes resulting in a global rearrangement of the transcription landscape (Figure S1).

Not only miRNAs but also tasiARFs were found to be differentially expressed in chilling-stressed condition, indicating a perturbed small RNA system that is potentially associated with the widely altered transcriptome.

Despite this finding, qualitative analysis by scanning electron microscopy did reveal altered trabecular architecture (widely spaced and thin trabeculae) in Mecp2stop/y mice, consistent with the overall osteoporotic picture and suggesting clear structural differences between genotypes which would be consistent with reduce bone integrity.

Additionally, the number of nutrients removed or altered through home or small-scale industry processing may vary widely.