Exact(3)
The fraction of the genome altered was calculated by summing the lengths of all regions with either amplification or deletion, as determined by ADM-2.
Relatedly, percent genome altered was calculated by adding the length of each "altered" segment, divided by the total length of the genome analyzed.
The proportion of the genome with copy number aberrations (proportion of the genome altered) was calculated for each case at baseline and utilized as an index of genomic instability.
Similar(57)
The percentage of the total population that was altered was then calculated for each morphant group.
The fraction of the genome altered (FGA) was calculated as described [ 14].
The fraction of the genome altered (FGA) was calculated as previously described [ 17].
The value on the mean of altered gene was calculated based on at least three independent microarrays.
The frequency of altered RAPD profiles was calculated for each liver lesion as reported (Luceri et al, 2000).
The probability that a particular biological process GO term was enriched in the input GO list (All GO annotations in the TRAITS-GS array) compared to the output GO list (all GO annotations in the experimentally altered gene list) was calculated using a hypergeometric distribution model as implemented by GeneSpring GX 7.3.1.
The fraction of the genome altered was determined by calculating the fraction of genes with fluorescence ratios ≥3 (for amplifications) or with significant non-zero fused lasso calls (for gains and losses).
The size in base pairs (bp) of the segmented regions altered (lost or gained) was calculated from the start and end position of the segments; (2) fraction of probes altered - proportion of probes showing loss, gain, and amplification; (3) number of altered segments identified - the total number of individual altered segments, lost or gained, was determined from the waviCGH segmented call data.
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