Sentence examples for altered utilization from inspiring English sources

These, together with the activation of hypoxia-inducible factor (HIF), a transcription factor that is activated by hypoxic stress but also by oncogenic, metabolic, and oxidative stress, often lead to the overexpression of the glucose transporters and various glycolysis pathway enzymes or isozyme subtypes explaining the increased glucose uptake and altered utilization [ 13, 14].

Simultaneous accumulation of free SUMO1 and SUMO2 was also observed in GSNO-challenged cells (Fig 1A), suggesting that overall hyposumoylation was attributed to altered utilization rather than reduced expression of SUMO1/2 modifier.

Furthermore, not even the presence of 25.5 mM glucose in the growth media was able to reverse the reduced rate of DNA synthesis of SCD1 deficient cells, suggesting that the abnormally low rate of replication of cells with reduced SCD1 can not be attributed to an altered utilization of glucose.

They do not exclude, however, that altered oxygen utilization can follow at a later stage.

Multiple mechanisms underlie DCM, including altered substrate utilization and energetics, oxidative stress, endothelial dysfunction, myocardial fibrosis, and myocyte apoptosis.

Neither single nor combined administration of VU0467154 with MK-801 altered serotonin utilization in the NAS and CP (data not shown).

Inflammation and other immune responses alter nutritional status through sequestration of minerals (eg, iron and zinc), impaired absorption, increased nutrient loss, or altered nutrient utilization.

Exogenous salicyl alcohol was readily glycosylated in Populus cell cultures, a process that altered sugar utilization and phenolic partitioning in the cells.

In view that glycolysis and PPP are two interconnected metabolic pathways, we then assessed whether the increase in glycolysis altered glucose utilization through the PPP.

This section first considers the limited direct neuroimaging evidence of altered energy utilization in the CNS of people with ADHD that could potentially derive from deficient astrocyte function [ 116].

Rimonabant-induced weight loss occurs through central effects in reducing food intake and through peripheral metabolic pathways (altered substrate utilization, changes in adiponectin, and changes in energy expenditure) (13).