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As this method did not allow measurement of the effect on individual RBC it was unclear what RBC properties were altered to induce this change.
The MAM domain (IPR000998) in neuropilin 1 (Nrepresentingenting adhesive function, may be altered to induce endothelial dysfunction in response to stress.
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Since it has been shown that Mtb possesses at least two active L,D-transpeptidases that catalyze the formation of non-classical linkages during the stationary phase of growth [17], [18], there is the possibility that overproduction of Rv2518c alone may be ineffective at creating a strain which contains a sufficient amount of altered peptidoglycan to induce protection against latent Mtb.
In addition to affecting gene expression, high glucose levels alter metabolism to induce the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS), which might be mediators of EC dysfunction (Fig 3) (Blake & Trounce, 2013).
Nevertheless, due to the fact that animal models typically do not contract the same genetic diseases as people, so scientists must alter their genomes to induce human disease states and to know what kind of mutation causes the disease.
Neutralization of LPS in these supernatants did not alter their ability to induce IFN-γ production (data not shown).
Taken together, these data suggest that 6 hours of HBO exposure do not directly affect PbA-infected erythrocytes nor alter their ability to induce CM clinical symptoms.
Within-cluster data dependence limits the use of classifiers such as Random Forest (RF) without first altering the data to induce independence, for example, averaging the observations obtained from technical replicates from the same subject [16].
Exchange of gene segments between high and low pathogenic IAVs is known to alter their ability to induce cell death.
HDAC inhibitors are exciting compounds with anticancer properties, altering gene expression to induce death, differentiation and/or cell-cycle arrest of tumor cells.
This idea was supported by a lab-scale fermentation experiment, where plasmid topology was shown to be similarly altered by conditions designed to induce metabolic stress.
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