The phrase "altered the potency of" is correct and usable in written English.
It can be used in contexts discussing changes in effectiveness, strength, or influence, often in scientific or analytical discussions.
Example: "The new formulation altered the potency of the drug, making it more effective in treating the condition."
Alternatives: "changed the effectiveness of" or "modified the strength of".
No phosphorylation site mutation altered the potencies of NPY or PYY BiFC responses, when these could be accurately measured.
While this may not alter the potency of the NK1 antagonists that have good blood-brain barrier permeability, it may increase the penetration of those NK1 antagonists that normally would not permeate an intact blood-brain barrier to the same degree.
Previously the STK15 (rs2273535, p.Phe31Ile) variant was found to alter the potency of STK15 transformation [27] and was reported to be associated with cancer risk in a number of cancer types including ovarian, colorectal, breast, oesophagus and lung [28] [31].
Importantly, cyanamide did not alter the potency of the NO donor Sper/NO, ruling out non-specific effects of this inhibitor on NO bioactivity.
Overexpression of the L. major nitroreductase did not alter the potency of (R)- or (S -PA-824 againS -PA-824ovani promaS -PA-824
Together, these data indicate that fluctuations in DAT levels/ Vmax are capable of altering the potency of all psychostimulants tested; however, the extent to which uptake inhibition is affected by Vmax differs across drugs.
As concurrent treatment of DEX (10 n M) failed to alter the potency of docetaxel, we conducted a further series of experiments examining the effect of pre-treating PC3 cells with DEX before docetaxel administration.
Although without effect in the absence of DADLE, co-addition of SB225002 (10−6 M) resulted in higher levels of DADLE-stimulated [S]GTP[S] binding without altering the potency of the opioid agonist (pEC50=−7.1).
Together, these data show that fluctuations in DAT levels alter the potency of releasers and MPH but not blockers and suggest an integral role of the DAT in the addictive potential of AMPH and related compounds.
In a systematic search for miRNAs mediating drug efficacy, miR-21 was identified as having the capacity to alter the potency of a wide range of chemotherapeutic agents by up to fourfold (Blower et al. 2007), which suggests that targeting miR-21 may enhance sensitivity to multiple chemotherapeutic drugs.
