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One is that the drug altered the functioning of other proteins in the brain and body -- it now appears that gamma secretase is involved in the production of about 20 proteins in addition to beta amyloid.
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Shortly thereafter, mutations that altered the function of the sclerostin (SOST) gene were also associated with altered human bone mass.
FRANK LLOYD WRIGHT never wrote as extensively about his patterned glass windows as he did about his architecture and building materials, even though his designs drastically altered the function of stained glass in architecture.
In the period following the Napoleonic Wars, several reformers altered the function of the "poorhouse" into the model for a deterrent workhouse.
These data support the ideas that Ndel1 is in complex with Vimentin in axons and neurons and the Ndel1 siRNA altered the functions of neuronal Vimentin.
Methylglyoxal activated peripheral nerves and altered the function of Nav 1.8, and Nav 1.7.
This implies that the ultramicro inversion had altered the function of the corresponding fibronectin type III domain.
It alters the functioning of social stigma, shame, and identity itself".
The right prefrontal cortex, for example, communicates with certain types of immune cells, and stress appears to alter the functioning of a chemical messenger, dopamine, in the region.
This effect would ultimately alter the functioning of the cancer cells, where the division of cancer cells can be blocked (Lobikin et al. 2012; Persinger and Lafrenie 2014).
The trick is achieving "knock down" by altering the functioning of targeted proteins within a designated cell -- no trivial task.
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CEO of Professional Science Editing for Scientists @ prosciediting.com