The phrase "altered the functionality of" is correct and usable in written English.
You can use it when discussing changes made to the way something operates or performs, often in a technical or software context.
Example: "The recent update altered the functionality of the application, improving its user interface and response time."
Alternatives: "changed the operation of" or "modified the performance of".
Furthermore, co-delivery of the GM-CSF DNA altered the functionality of HA-specific T cells but this effect markedly differed between the two compartments.
Furthermore, resveratrol is susceptible to in vitro oxidation under normal oxygen conditions [ 33], so it is possible that the hyperoxygenated environment used in these experiments altered the functionality of resveratrol enough to prevent lifespan extension.
These alterations may subsequently alter the functionality of the ASV as compared with the engineered or metalloprotease-generated soluble receptors.
The interfacial coatings around lipid droplets can be tailored in a number of ways to alter the functionality of emulsion-based delivery systems.
While the functional output of the core product is identical across the products, product variety is created using add-on services that do not alter the functionality of the core product.
In contrast, natural disasters are natural hazards that severely and negatively alter the functionality of the social environment or infrastructure (Alcántara-Ayala 2002 IPCCC 2012).
Another possibility would be that the observed changes in the protein-to-cardiolipin ratio alter the functionality of the respiratory chain and/or the assembly of respiratory complexes in R1H cells.
Since the treatments did not alter the levels of expression of this protein, this increase must occur through mechanisms that alter the functionality of ERα.
The increased proliferative capacity of ER+ breast cancer cells subjected to mild nitrosative stress therefore arises through mechanisms altering the functionality of ERα and/or p53.
