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Shortly thereafter, mutations that altered the function of the sclerostin (SOST) gene were also associated with altered human bone mass.
FRANK LLOYD WRIGHT never wrote as extensively about his patterned glass windows as he did about his architecture and building materials, even though his designs drastically altered the function of stained glass in architecture.
We reasoned that KBU2046 was binding to either CDC37 or HSP90β, that this altered the function of the CDC37/HSP90β heterocomplex resulting in a change in the spectrum of bound client kinase proteins, that changes were highly selective and that this altered binding spectrum would in turn be responsible for KBU2046's effects upon cell motility.
Lactate decreased IL-12 production from mouse intracranial glioma derived DCs stimulated by R848, and even altered the function of the agonist, which resulted in the activation of STAT-3 signaling in DCs and subsequent suppression of their maturation.
In the period following the Napoleonic Wars, several reformers altered the function of the "poorhouse" into the model for a deterrent workhouse.
The central role of NFκB in disposal of the microbe suggests that pharmacological manipulations that altered the function of this transcription factor could have a profound effect on clearance of this organism.
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Mutations, which are less common, often cause disease by altering the function of a key protein.
These changes alter the function of the targeted gene facilitating the analysis of gene function.
I always ask patients about their use of alternative medicines because these substances may alter the function of many organs, especially the thyroid.
"We managed to alter the function of this gateway so that these proteins can no longer get into the red blood cells, starving and killing the parasite".
This concept allows re-configuration of the control without altering the function block diagram.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com