Sentence examples for altered the activation of from inspiring English sources

We further examined if the CM from co-culture of MLE-12 and Raw264.7 cells could activate fibroblasts, and if Ninj1 deficiency in these two cell lines altered the activation of fibroblasts.

These alterations could have modified the activity of receptors in cell membranes, thus altering the activation of intracellular pathways and downstream regulatory proteins, such as those related to the IGF-1/PI3-K/Akt/mTOR pathway, which are compartmentalized and activated through their translocation to the plasma membrane [ 52].

Vitamin D3 upregulated protein-1 regulates proliferative signaling during liver regeneration by altering the activation of genes involved in the extracellular signal-regulated kinase 1/2 and AKT signaling pathways (Kwon et al., 2011).

Interference with the ERK1/2 cascade with PD98059 did not alter the activation of moesin (Fig. 4B C).

The aim of the present study was to determine whether modulation of the parasite load within a certain period of time can in fact alter the activation of effector/protective CD8+ T cells.

Calcium can also mediate apoptosis by altering the activation of cell surface death receptors and caspases.

In addition, ActRIIB treatment of immobilized mice also did not alter the activation of Smad2 or Smad3 (Fig. 2A).

Furthermore, treatment with siRIP3 did not alter the activation of caspase-8, but instead increased activation of caspase-9 and promoted endonuclease G translocation into OHC nuclei.

Even binding specific receptors as ligands can alter the activation of other receptors through cross-talk mechanisms, or impairment of hormone biosynthesis through feedback pathways.

The results indicate that MEKK1, MEKK2 and MEKK3 deficiency do not alter the activation of JNK, p38 or ERK in IL-1β-stimulated FLSs.

These findings suggest that arsenic exposure may alter the activation of CD4 T cells resulting in reduced cytokine secretion and immune suppression.