The phrase "altered substantively" is correct and usable in written English.
It can be used in contexts where you want to indicate that something has been changed in a significant or meaningful way.
Example: "The document was altered substantively to reflect the new policies implemented by the organization."
Alternatives: "changed significantly" or "modified meaningfully".
This finding is consistent with the fact that policy concerning the granting of the Family Stream visas did not alter substantively over the associated time period (discussed in Section 2).
In such a scenario, to ensure that the subjects of our case studies are not trivially traceable (through, for instance, a simple Google search), we slightly altered (without substantively changing) the text of any content that we reproduced verbatim.
Editor's note: a number of minor editorial changes were made after publication at the request of the authors; none substantively altered the meaning of the article.
Certainly, there have already been complex traits-ones undoubtedly shaped by many genes-that can be substantively altered by changing one gene.
Those researchers declined to guess at who might be pulling the strings of the vast botnet, but did say that they did not believe it "substantively altered" the tenor of the campaign.
This American Life may have since reclaimed the top spot, but Welcome To Night Vale remains a top five regular, though success hasn't altered the podcast substantively; it remains free to download, and free of advertisements, thanks to donations from fans.
It looks like our financial regulatory system substantively altered in the Bear Stearns, JPMorgan meetings.
The Malaysian government hasn't substantively altered any of its labor policies in the year since the Verite report was published, although some companies have announced changes in corporate policies.
Similarly, when the veterinary assessors were included in the model as fixed effects the parameter estimates were not substantively altered.
