Sentence examples for altered stem cells from inspiring English sources
The altered stem cells also matured and, as hoped, diversified into different types of immune system cells that HIV infects.
Constant proliferation is a vital feature of stem cells, and in gastrointestinal tissues mutations are likely to result in expansion of altered stem cells, increasing the probability of additional mutations and tumor progression [ 12].
As humans and other organisms age or experience external insults such as radiation or smoking, the structure and function of tissues progressively degrade, resulting in altered stem cell niche microenvironments.
It is not yet known whether extension of sensory neuropathy to the BM may contribute to altered stem cell release.
We were unable to directly attribute any of these effects to loss of epidermal stem cells or altered stem cell proliferation.
Patches of genetically altered stem cell clones develop into individual fields that eventually mature into contiguous pastures of precancerous cells [ 28].
Prenatal TBT exposure is thus a maternal programming event that permanently altered stem cell fate leading to a reproducible adult phenotype.
Modestly altered stem cell pools in certain tissues of p53 mutant mice have been reported to be affected by age (Dumble, 2007).
And as described above, altered stem cell fitness should increase selection for adaptive oncogenic mutations, increasing the chances that stem cells bearing particular oncogenic mutations expand within competitive HSC pools in an aged bone marrow microenvironment.
This is the first known study to show that prenatal exposure to low, environmentally relevant concentrations of an obesogen led to transgenerational effects on white fat volume, altered stem cell programming, and liver fat accumulation in multiple generations of mice.
Another, already used to eradicate tumors in mice, uses gene therapy to alter stem cells, which in turn make immune cells that combat the specific cancer – a treatment that would last a lifetime.
