Sentence examples for altered stem cell from inspiring English sources

As humans and other organisms age or experience external insults such as radiation or smoking, the structure and function of tissues progressively degrade, resulting in altered stem cell niche microenvironments.

It is not yet known whether extension of sensory neuropathy to the BM may contribute to altered stem cell release.

Patches of genetically altered stem cell clones develop into individual fields that eventually mature into contiguous pastures of precancerous cells [ 28].

Prenatal TBT exposure is thus a maternal programming event that permanently altered stem cell fate leading to a reproducible adult phenotype.

We were unable to directly attribute any of these effects to loss of epidermal stem cells or altered stem cell proliferation.

Modestly altered stem cell pools in certain tissues of p53 mutant mice have been reported to be affected by age (Dumble, 2007).

In a second section, we will emphasize in the mammalian epigenetic alterations and how they may affect human longevity by altering stem cell function and/or somatic cell decline.

In mice, even mild maternal illness during early pregnancy can alter stem cell activity in the developing fetal brain.

Gene editing offers unprecedented opportunity to alter stem cell genomes to make lasting cures for monogenic disorders, including countless rare diseases.

However, the therapy did not appear to alter stem cell methylation patterns, suggesting stem cells are protected from this type of therapy.

Functional studies demonstrated that certain factors which increase their expression during aging could functionally impair stem cell function, adding to the body of work that age-associated inflammatory signals might contribute to aging by altering stem cell function [ 6].