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However, the report implicating serotonin in GRP specification suggested that inhibition of serotonin signaling causes serious patterning defects in treated embryos, including altered specification of the superficial mesoderm (Beyer et al., 2012), a phenotype we never observed with our reagents but one that could potentially contribute to non-specific laterality defects due to toxicity.
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Many of the gene variants identified in this way are likely to alter specification and maintenance of neuronal connections.
The neural network prediction accuracy was fed back to the optimisation algorithm, which altered the specification of the competition index based on changes in the prediction accuracy.
Reduced CC10 expression in Hoxa5−/− embryos indicates that altered cell specification occurs prior to birth.
They allow unambiguous uncoupling of Met requirements for axonal growth from muscle development, and they also allow distinguishing of a nerve pattern defect from the consequences of an altered MN specification process (unlike for brachial Pea3 MN pools).
On the other hand, preferential suppression of either miR-9 or miR-9* would be predicted to alter the ratio of REST to coREST, which has important and complex consequences for neural stem-cell renewal and altered lineage specification (Abrajano et al. 2009, 2010).
TRW beat the Lockheed Martin Corporation for the contract, which was postponed several months as the National Aeronautics and Space Administration altered some specifications to keep the telescope within budget.
2) It is unclear to this reviewer that the observation of Tbr+ cells in the EGL and ML of Nf1/Math1 CKO mice proves that loss of NF1 causes altered fate-specification.
The arthropod Esyt2 genes include mutually exclusive alternative exons which serve to alter the specification of the first C2 domain.
A way to go around this and be able to re-bid that day is to alter your specification options.
Follow either the general recommended cooking specifications based on the type of baked good, or alter the specifications mentioned in the recipe based on the alteration guidelines.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com