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Hierarchical clustering using the significantly altered set of 10 miRNAs showed a clear separation between alive and dead subjects).
Based on these experiments, the general idea is that when a group of cells separate from an existing cell layer, the segregating cells express a qualitatively or quantitatively altered set of cadherin family members.
But if a newer, better and perhaps even more complex form of that structure should evolve, suiting the descendant species even better to a slightly altered set of environmental circumstances, it will be conserved.
In addition, chronic abuse of substances leads to an altered set point across multiple systems.
Persistent challenges to an organism through chronic substance use may ultimately lead to an altered set point across multiple systems.
Chronic, heavy use of ethanol produces an allostatic state wherein reinforcing and stress-provoking effects of the drug battle and oppose each other but generally contribute to an altered set point below that associated with normal mood states.
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Disruption to insulin-like growth factor (IGF) signalling pathways during early life causes growth retardation and defects of developing metabolic organs that can alter set points of energy homeostasis for a lifetime.
The altered set-up may have put HMV on a surer footing, but some analysts argue that the retailer is not out of the woods.
Calculation of the flux distribution with randomly altered set-point concentration values was repeated in 1000 trials.
In healthy volunteers, rs10994336 may be associated with reduced white matter integrity in the anterior limb of the internal capsule, as well as with altered set-shifting and decision-making 48.
Meyer and cinematographer Hiro Narita aimed for a darker and more dramatic mood, subtly altering sets originally used for the television series Star Trek: The Next Generation.
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