The upstream sequence of pCH201 was altered to separately incorporate the following mutations: UGU or UUG as the -1 triplet, U85A, and A86C.
We have subsequently designed and assessed the replication phenotypes and fitness of mutants of E7 constructed in such a way that allows effects of codon pair and dinucleotide frequency alterations to be separately altered.
Z-score plots, displaying the levels of altered metabolites, were separately generated to compare both experimental groups and the control group.
The odds of mortality for each year were altered when adjusted separately for each of the potential confounders of age, sex, and Charlson index.
The function of these motor nuclei is not easy to determine with standard behavioral testing, for example studies of ability to eat (a test of trigeminal, facial, glossopharyngeal, vagus and hypoglossal nerve function) are confounded by affect, appetite or general mobility, which may be separately altered in neurodegenerative disease.
None of the above risk estimates was attenuated when we restricted the analysis to children with two non-Hispanic white parents, nor were they markedly altered when we separately used either the interviewed controls identified through RDD or the anonymous WDOH archive controls as the reference group.
These relationships were not altered substantially when examined separately by age-group or sex.
We also tested whether improved sequence assemblies could be generated by separately altering certain Phrap parameters.
Because the evolution of male and female traits are treated separately, mutations for altered maternal care always occur in the presence of constant resident paternal care zm, and we can therefore omit paternal care from the survival functions.
Having modules that have achieved degrees of validation separately and can be easily altered, both alone and when composed, will increase the pace toward better mechanistic explanations.
DAVID and PathVisio analyses for pathway enrichment were performed first for all significantly altered genes, then for up- and down-regulated genes separately.
