There were also disruptions in a number of other coding exons (see Additional file 1), indicating that SMAD4 was also altered in the human tumors, consistent with previous studies [ 25- 27].
Our results suggest that septum morphology is altered in the conditional mutant; interestingly, a previous study showed that septin mutants of C. albicans (particularly the cdc10Δ null mutant) displayed defects in cytokinesis, diffuse mislocalization of chitin, and increased axial bud scars (35).
As in numerous previous studies, we found that the apoptotic pathway was altered in the patients.
Most previous explanations had focussed on explaining how someone's beliefs might be altered in the moment.
We evaluated regression models of ego happiness as a function of ego's age, sex, education, and happiness in the previous exam, and of the happiness of an alter in the current and previous exam.
As this is a delicate issue, the discussion has been appropriately altered In a previous paper (Neuberger et al., Biology Direct, 2007, 2, 1), it was reported that PKA phosphosites tend to be surrounded by a region with a trend towards small, flexible and more polar amino acid residues.
In the control arm, screening visit procedures were not altered from the previous routine.
Our analyses confirmed the main biological GO terms found altered in previous blood transcriptomics of PD patients.
To test the relation more rigorously, we specified generalised estimating equation regression models of ego happiness with the number of happy and unhappy alters in the previous exam as key predictors.
Levels of the proinflammatory cytokine TNF-α were not altered, in keeping with previous studies [ 15, 18, 60].
Several of the regions have also been identified as frequently altered in previous CGH studies of MFHs, and may be characteristic for this type of tumours, although not necessarily specific.
