The phrase "altered in hypothalami of" is correct and usable in written English.
It can be used in scientific or medical contexts when discussing changes or modifications that occur in the hypothalamus of an organism.
Example: "The results indicated that the gene expression was significantly altered in hypothalami of the experimental group."
Alternatives: "modified in the hypothalamus of" or "changed in the hypothalami of".
Gene set enrichment analysis in hypothalami of mice with sodium appetite showed significant enrichment of gene sets previously linked to addiction (opiates and cocaine).
We determined the expression of Nhlh2 by in situ hybridization in hypothalami of embryonic and adult Nkx2.1iCre/+ Ngn3 flox/flox mutants.
The expression of genes coding for the appetite-modifying peptides MCH and orexin A was up-regulated in hypothalami of HP mice.
The key role of this neuropeptide in integrating the downstream effects of leptin is demonstrated by the fact that MCH expression is increased in hypothalami of ob/ ob mice, with a dramatic reduction in body fat seen in ob/ ob mice also lacking MCH.
None of these photos were altered in any way.
To examine whether protein expression in the hypothalamus was altered in tumour-bearing anorexic mice compared with free-fed control mice and caloric-restricted pair-fed mice, extracts from the hypothalami were separated by high-resolution two-dimensional electrophoresis (2-DE) using three different narrow pH range IPG strips (IPG 3 6, IPG 5 8, and IPG 7 10; experiment 1).
Solt et al. report the identification of potent synthetic REV-ERB agonists, termed SR9011 and SR9009, which can alter the circadian expression of core clock genes in the hypothalami of mice.
Consistent with food intake, AICAR increased AMPK threonine and ACC serine phosphorylation levels in the hypothalami of control rats, whilst in exercised animals, AICAR did not change AMPK/ACC phosphorylation status (Figures 3b and c).
Increased hexokinase expression in the hypothalami of tumour-bearing mice in the present study is apparently a cancer-related process because the expression of that protein in pair-fed animals was similar to that in the free-fed group.
This observation may suggest that increased EP4 receptor signalling could be another possible reason for the increased dynamin 1 expression in the hypothalami of tumour-bearing mice in the present study.
