The phrase "altered in cancers of" is correct and usable in written English.
It can be used in a scientific or medical context when discussing changes or modifications that occur in various types of cancer.
Example: "The gene expression patterns altered in cancers of the breast and lung have been extensively studied."
Alternatives: "modified in cancers of" or "changed in cancers of".
Thirdly, the O-linked glycosylation of MUC1 is drastically altered in cancer when truncation of the O-linked glycans is observed 37.
Furthermore, lipid metabolism is altered in cancer, including loss of body fat early in tumor growth, induction of hyperlipidemia and changes in a variety of serum lipid and lipoprotein fractions.
The observation that the regulation of the human metabolic network is under the control of signaling pathways often altered in cancer has shifted a lot of attention to cancer metabolism [ 17].
Furthermore this approach has permitted the identification of proteins or receptors which are altered in cancer, such as up-regulation of β1-integrin, with reversion to a normal phenotype when the actions of this integrin are blocked [ 13].
Moreover, Miyagi et al. have also reported that plasma levels of Gln, Trp, His, Pro, and Orn are commonly altered in cancer patients with five types of cancer (lung cancer, gastric cancer, colorectal cancer, breast cancer, and prostate cancer) [ 34].
The phosphatidylinositol 3-kinase (PI3K) pathway is frequently altered in cancer and is a focus of interest in ER + BC.
Our hypothesis is that apoptosis is altered in cancer patients due to resistance of Bcl-XL to p53-independent stimulation by Myc (MAX), potentially Bax, or other BH3-only proteins.
The mitochondrial membrane permeabilization (MMP) process is often altered in cancer cells possibly as a result of PTP component overexpression [19], upregulation of anti-apoptotic members of the Bcl-2 family and/or downregulation of Bax [20].
While gene expression studies are useful in identifying broad categories of pathways altered in cancer and clinically important subtypes [2], on their own they may not be able to distinguish the genetically altered key driver genes.
DNA dosage is frequently altered in cancer and is an important determinant of mRNA expression.
