The phrase "altered in brains of" is correct and usable in written English.
It can be used when discussing changes or modifications that occur within the brains of individuals or organisms, often in a scientific or psychological context.
Example: "The study revealed that certain chemicals can be altered in brains of individuals suffering from depression."
Alternatives: "changed in the brains of" or "modified in the brains of".
Expression of BDNF, DLX5 and FXYD1, proteins that mediate neural plasticity have been shown to be altered in brains of RTT patients and MeCP2 mutant mice [14] [19].
We further show that the inhibition of Sp1 binding to DNA, by mithramycin, modulates the expression of NDUFV2, NDUFV1, NDUFS1 and RELN (reelin), all reported to be altered in brains of schizophrenic patient.
Interestingly, a subset of mir-26a-5p potential genes target, selected by "MicroRNA Target Filter" program from IPA, were implicated in Glutamate Receptor Signaling metabolism (Table 3), which is altered in brains of multiple sclerosis patients [ 15].
To determine whether Crif1 level is also altered in brains of AD patients, quantitative real-time PCR (qRT-PCR) and WB analyses in the superior temporal cortex of human brains, showed a reduction in Crif1 mRNA and protein levels in AD patients, as much as 35% and 21%, respectively, compared with control brains.
IL-2, IL-4, IL-10, IL-12p70, IL-17, IFN-γ, TNF-α, IL-18 and IL-33 were not altered in brain homogenates of mice with pneumococcal meningitis compared to sham controls.
Finally, we found that AChE levels were altered in brain and spleen of prion-infected mice and also in infected cell cultures compared to non-infected controls.
One alternative approach focuses on manipulations of mitochondria and energy metabolism, both of which are altered in the brains of AD patients (Swerdlow, 2014).
Considering the NMDA receptor hypofunction hypothesis for schizophrenia [19] [23], it is of great interest to study whether levels of GSH are altered in the brains of schizophrenic patients.
These coordinated patterns of activity are often altered in the brains of patients with neurological or psychiatric disorders.
Our data demonstrate that the neuronal distribution and levels of VPS35 protein are not altered in the brains of PD or DLB subjects.
We first investigated whether NLRP1 expression is altered in the brains of APP/PS1 mice overexpressing the Swedish mutation of APP together with PS1 deleted in exon 9. Total proteins were extracted from the cortical and hippocampal regions of 3-, 6-, and 9-month-old APP/PS1 and age-matched wild-type mice, and subjected them to western blot analysis.
